COALESCENT THEORY WAKELEY PDF

The theory was initially developed by Kingman in 3 papers published in probability theory journals, which outline the foundation of coalescent theory as a suite of probability models. Recent publications continue to address the mathematical development of the coalescent in mathematical journals e. The 2 important points to take from these facts are that, first, coalescent theory is still an active and exciting topic that continues to be developed in its fundamentals and applications and, second, that any book on coalescent theory is going to be heavy on the mathematics. The new book by John Wakeley aims to summarize the fundamentals of coalescent theory, and it certainly fits the second expectation. This book provides a walk through the mathematical derivations of major aspects of coalescent theory and some specific applications in population genetics.

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Coalescent theory provides the foundation for molecular population genetics and genomics. As an informative and useful text, Coalescent Theory focuses on why this theory is the conceptual framework that makes studies of DNA sequence variation within species possible and how it works as a tool for making inferences about mutation, recombination, population structure and natural selection from DNA sequence data.

He has worked extensively in coalescent theory. His research has focussed on populations structured by geography and limited migration. Using coalescent models, Dr. Wakeley has addressed questions about the current and historical demography of humans and other species. In May , Dr. Support back Get Help Support Community.

Rental FAQs. Read and study old-school with our bound texts. About Contents Authors About. Table of Contents. Gene Genealogies 2. Probability Theory 3. The Coalescent 4. Neutral Genetic Variation 5. The Structured Coalescent 6. Separation of Time Scales 7. Ancestral Graphs 8. Simulations and Inference Bibliography Index. Related Titles. Find Your School. No active courses are available for this school.

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Coalescent Theory

If you are affected please select an ebook version instead. Apologies for the inconvenience. John Wakely. Recommend to library. This textbook provides the foundation for molecular population genetics and genomics. It shows the conceptual framework for studies of DNA sequence variation within species, and is the source of essential tools for making

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Coalescent theory provides the foundation for molecular population genetics and genomics. As an informative and useful text, Coalescent Theory focuses on why this theory is the conceptual framework that makes studies of DNA sequence variation within species possible and how it works as a tool for making inferences about mutation, recombination, population structure and natural selection from DNA sequence data. He has worked extensively in coalescent theory. His research has focussed on populations structured by geography and limited migration. Using coalescent models, Dr. Wakeley has addressed questions about the current and historical demography of humans and other species. In May , Dr.

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Coalescent theory provides the foundation for molecular population genetics and genomics. It is the conceptual framework for studies of DNA sequence variation within species, and is the source of essential tools for making inferences about mutation, recombination, population structure and natural selection from DNA sequence data. The case studies are a terrific feature I think many biologists will be greatly buoyed by these, and motivated to think deeper about the models and how they can be analyzed. A must for everyone interested in ancestral population genetics. Students and teachers will welcome this accessible treatment. For the first time, Wakeley's book provides a clear and accessible account of this key subject, which takes the reader right up to the frontiers of current research.

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