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These metrics are regularly updated to reflect usage leading up to the last few days. Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts. The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.
Find more information on the Altmetric Attention Score and how the score is calculated. The sample is focused in the first capillary by ITP and injected repeatedly into the second smaller diameter capillary for more rapid CZE separation.
Since only small portions of the concentrated zones are sequentially injected for CZE separation, overloading was not observed. Moreover, the sensitivity is enhanced because all of the concentrated zones are analyzed and the results are summed.
The system was evaluated using a mixture of angiotensins. View Author Information. Cite this: Anal. Article Views Altmetric -. Citations Cited By. This article is cited by 40 publications. Wyatt N.
Vreeland,, Stephen J. Williams,, Annelise E. Barron, and, Alexander P. Analytical Chemistry , 75 13 , Capillary Electrophoresis for the Analysis of Biopolymers. Analytical Chemistry , 74 12 , Fraga,, Carsten A. Bruckner, and, Robert E. Analytical Chemistry , 73 3 , Multiple capillary isotachophoresis with repetitive hydrodynamic injections for performance improvement of the electromigration preconcentration.
Journal of Chromatography A , , Simpson, Kun Liu, Paul B. Farnsworth, Stanley D. Stearns, Milton L. Instrumentation for hand-portable liquid chromatography. Kler, Tjorben N. Posch, Martin Pattky, Roald M. Tiggelaar, Carolin Huhn. Column coupling isotachophoresis—capillary electrophoresis with mass spectrometric detection: Characterization and optimization of microfluidic interfaces.
Stacking and simultaneous determination of estrogens in water samples by CE with electrochemical detection. Journal of Separation Science , 36 2 , Capillary Electrophoretic Separations.
Electroosmotic flow-balanced isotachophoretic stacking with continuous electrokinetic injection for the concentration of anions in high conductivity samples. Journal of Chromatography A , 24 , Ultrasensitive determination of cobalt in single hair by capillary electrophoresis using chemiluminescence detector. Microchemical Journal , 95 1 , A microfabricated CE chip for DNA pre-concentration and separation utilizing a normally closed valve. Rapid and efficient isotachophoretic preconcentration in free solution coupled with gel electrophoresis separation on a microchip using a negative pressure sampling technique.
Journal of Chromatography A , 20 , Pierce, Jamin C. Hoggard, Rachel E. Mohler, Robert E. Recent advancements in comprehensive two-dimensional separations with chemometrics. Sample preparation. CE for cytokinin analyses: A review. Determination of trace cationic impurities in butylmethylimidazolium-based ionic liquids: From transient to comprehensive single-capillary counterflow isotachophoresis-zone electrophoresis.
Analysis of cytokinin nucleotides in coconut Cocos nucifera L. Determination of cytokinins in coconut Cocos nucifera L. On-line preconcentration of protein in capillary electrophoresis with an end-column cellulose acetate-based porous membrane.
Journal of Chromatography A , 2 , Prest, Peter R. Fielden, Nicholas J. Goddard, Andreas Manz, Philip J. Miniaturised isotachophoresis analysis. Lab on a Chip , 6 4 , Electrophoretic analysis of gold nanoparticles: size-dependent electrophoretic mobility of nanoparticles. IEE Proceedings - Nanobiotechnology , 3 , On-line cation-exchange preconcentration and capillary electrophoresis coupled by tee joint interface. Discontinuous electrolyte systems for improved detection of biologically active amines and acids by capillary electrophoresis with laser-induced native fluorescence detection.
Coupling continuous flow systems to capillary electrophoresis. On-line sample concentration techniques in capillary electrophoresis: Velocity gradient techniques and sample concentration techniques for biomolecules.
Capillary electrophoresis for the determination of drugs in biological fluids. Mobility-based selective on-line preconcentration of proteins in capillary electrophoresis by controlling electroosmotic flow. Journal of Chromatography A , 1 , Enhancing sensitivity in capillary electrophoresis. Microfluidic separation of DNA. Current Opinion in Biotechnology , 14 5 , Direct determination of valproate in serum by zone electrophoresis-isotachophoresis on a column-coupling chip.
Journal of Separation Science , 26 8 , Advantages and limitations of coupling isotachophoresis and comprehensive isotachophoresis—capillary electrophoresis to time-of-flight mass spectrometry. High-sensitivity capillary gel electrophoretic analysis of DNA fragments on an electrophoresis microchip using electrokinetic injection with transient isotachophoretic preconcentration.
New approaches to sample preparation for capillary electrophoresis. Sample pre-concentration by isotachophoresis in microfluidic devices. Journal of Separation Science , 25 3 , Chapter 29 Sample cleanup and concentration techniques for capillary electrophoresis. Recent advances in capillary electrophoresis of peptides. Capillary zone electrophoresis of orotic acid in urine with on-line isotachophoresis sample pretreatment and diode array detection.
Automated Free-Solution Isotachophoresis: Instrumentation and Fractionation of Human Serum Proteins
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Isotachophoresis, Volume 6
An automated free-solution isotachophoresis system FS-ITP for preparative fractionation of biopolymers is described, operated in a batch mode. The dimension of the separation chamber allows an up to fold higher sample load compared to separation in capillaries of microm inner diameter as used in analytical capillary isotachophoresis C-ITP. The preparative capacity of the system is within the milligram range. The method is fully compatible with analytical C-ITP, which is essential for preparative-scale isotachophoresis with regard to optimization of electrolyte systems and the search for suitable spacers. As a model application the fractionation of human serum proteins is reported.